Sermorelin injections are a synthetic version of growth hormone-releasing hormone (GHRH), a naturally occurring hormone involved in signaling the pituitary gland to release growth hormone into the bloodstream. Olympia’s compounded Sermorelin Acetate is a featured product in our Weight Management line of medications.
Sermorelin injections may be prescribed in cases where a clinician is evaluating or addressing growth hormone production. Sermorelin injections can be administered by subcutaneous (SubQ) or intramuscular (IM) injection, depending on your prescriber’s direction.
Important note on sermorelin dosage
Important: Sermorelin dosing is individualized and will vary depending on patient needs and the plan created with a licensed healthcare professional. Use the dosage chart below as an educational overview only.
This blog is for informational purposes only and is not intended to substitute for medical advice. Always follow your prescription label and your prescriber’s instructions.
Quick sermorelin dosage chart (0.9 mg/mL)
Dosage chart for Olympia Pharmaceuticals’ Sermorelin Acetate 0.9 mg/mL liquid injection showing 300 mcg (33 units) nightly dosing.
Concentration: 0.9 mg/mL (Sermorelin Acetate)
Routes: SubQ or IM (per prescriber direction)
| Week | Typical dose | Frequency | Notes |
| Week 1 | Inject 300 mcg (33 units) | Once nightly | Sixty to ninety minutes after your last meal |
| Week 2 | Inject 300 mcg (33 units) | Once nightly | Sixty to ninety minutes after your last mealFollow prescriber direction for any adjustments |
| Week 3+ | Inject 300 mcg (33 units) | Once nightly | Sixty to ninety minutes after your last mealOne vial is intended to cover 28 days at this schedule |
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Sermorelin dosage per day: why “once nightly”
The dosing guide above lists a typical plan as 300 mcg once nightly, 60 to 90 minutes after your last meal. In practice, “once nightly” usually means one injection in the evening each day, based on the schedule your clinician has selected.
If it helps to visualize weekly totals (as an example only):
- 300 mcg per night x 7 nights = 2,100 mcg per week (2.1 mg per week)
Your prescriber may keep the dose consistent or adjust it based on your goals, your response, and your overall protocol.
This schedule is recommended because Sermorelin is designed with support of the growth hormone-releasing hormone (GHRH) in mind. In the body, growth hormone is released in pulses, and these peak during the night. Administering Sermorelin before bed is intended to help synergize with your body’s own schedule of growth hormone release.
How to read the chart: mcg, mL, and “units”
Many dosing charts show mcg (the medication amount) alongside units (the markings on a common U-100 insulin syringe). This helps patients measure volume more easily.
Here is how the math works for Sermorelin Acetate 0.9 mg/mL:
- 0.9 mg/mL = 900 mcg/mL
- 300 mcg ÷ 900 mcg/mL = 0.333 mL (about 0.33 mL)
- On a U-100 syringe, 1 mL = 100 units, so 0.33 mL is about 33 units
Quick conversion tips (U-100 syringes):
- Units to mL: units ÷ 100 = mL
- mL to mcg (for 0.9 mg/mL): mL x 900 = mcg
Always verify two things before measuring: (1) your vial concentration on the label, and (2) the syringe type you are using. If anything looks different from this guide, pause and contact your prescriber or pharmacist.
SubQ vs IM administration
Sermorelin injections may be administered via subcutaneous (SubQ) or intramuscular (IM) injection, depending on the plan created by your clinician. Your prescriber may consider factors like your routine, comfort with injection technique, and how your overall protocol is structured.
If you have questions about technique, ask your medical team for training before your first dose.
What are Sermorelin injections prescribed for?
Patients who are experiencing low levels of human growth hormone (HGH) may be prescribed Sermorelin Acetate, though it can also be recommended for patients focusing on weight loss and athletic performance. Ultimately, your clinician can help determine whether Sermorelin fits your needs and how it should be dosed and scheduled.
Precautions and possible side effects
Like any medication, Sermorelin may cause side effects. These can include, but are not limited to, pain, redness, or swelling at the place of injection.
Not all individuals are good candidates for Sermorelin. Patients with an underactive thyroid or certain other medical conditions should consult their provider. Always inform your healthcare provider of all medications and supplements you’re taking.
Seek urgent medical care if you think you are having a serious allergic reaction.
Storage and handling notes
Store compounded Sermorelin injections under refrigeration and protect from light. Always read the label of your medication prior to administering an injection.
Resources
- Tutorial: How to Give a Subcutaneous Injection
- Tutorial: How to Open Your Medication Vial
Want to learn more about Sermorelin injections?
If you have questions about Sermorelin dosing, measuring units, or how this medication fits into a broader protocol, our team can help you understand what to expect and how to follow your prescriber’s instructions.
Educational use only. This content is not intended to replace advice from a licensed medical provider. Dosing examples and conversions in this post reference Olympia Pharmaceuticals’ compounded Sermorelin Acetate 0.9 mg/mL liquid injection only, and should not be used in reference to sermorelin prepared or compounded by other facilities.
All compounded formulations are prepared by Olympia Pharmaceuticals under cGMP practices and with oversight by national and state pharmacy boards.
