NAD+ Injections

NAD+ injections are a compounded prescription form of NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in every cell. They’re given by IV infusion, intramuscular (IM) injection, or subcutaneous (SubQ) injection, and are prescribed by healthcare providers as part of longevity and wellness care plans.

It depends on the route. Your provider will set your schedule based on:

Research on NAD+ and women’s fertility is emerging, but more must be conducted before any conclusive claims can be made. Some animal and laboratory studies suggest that it may support egg quality and mitochondrial health, which in turn could help with fertility, but we do not have enough clinical evidence to recommend it specifically for this purpose.

Despite popular belief, NAD+ is not a peptide; it’s a coenzyme derived from niacin, also known as vitamin B3. Peptides are short chains of amino acids, while NAD+ is a nucleotide-based molecule that’s involved in cellular metabolism.

Research suggests that NAD+ is a key factor in healthy aging. Higher NAD+ levels in the body play a role in supporting DNA repair, mitochondrial health, and sirtuin activation – all of which are associated with improved cellular resilience. Human studies are ongoing for further findings with NAD+, but the early research is promising.

NAD+ injections can be given three ways: 

• IV infusion: diluted in saline and infused slowly in a clinical setting, typically over 2 to 4 hours 
• Intramuscular (IM): injected into a muscle 
• Subcutaneous (SubQ): injected just under the skin, often at home after instruction from a provider. Read our guide on how to give a subcutaneous injection. 

Your provider will recommend the route that fits your care plan.

With IV infusions, commonly reported side effects include flushing, nausea, headache, chest tightness or pressure, abdominal discomfort, and lightheadedness. These are often related to infusion speed and typically ease when the infusion is slowed. With IM and SubQ injections, the most common side effects are redness, swelling, or soreness at the injection site. 

Contact your provider if side effects are severe or don’t go away. Seek emergency care for signs of an allergic reaction, such as trouble breathing, hives, or swelling of the face or throat. 

NAD+ injections aren’t right for everyone. Talk with your provider before starting if you: 

• Are pregnant, planning to become pregnant, or breastfeeding, as safety data is limited 
• Have had an allergic reaction to NAD+ or any ingredient in the formulation 
• Have a chronic medical condition, such as heart, liver, or kidney disease 
• Take prescription medications or other supplements 

Yes, NAD+ injections require a prescription. Like all compounded medications, they are not FDA-approved, meaning they have not gone through the FDA’s drug approval process for any specific condition. Because of this, insurance typically does not cover them.  

Quality instead depends on the compounding pharmacy you source it from. Olympia prepares NAD+ injections under state board of pharmacy oversight and at federal cGMP standards. Your prescribing provider will also monitor your regimen and adjust your plan as needed. 

The main difference is how NAD+ gets into the body. Oral supplements usually contain NAD+ precursors, such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which the body converts into NAD+ after digestion. NAD+ injections deliver NAD+ directly by IV, IM, or SubQ injection, bypassing the digestive system. To see how injections compare with supplements, read oral vs. injectable NAD+.

Oral supplements are typically available over the counter, while NAD+ injections require a prescription. Your provider can help you decide which option fits your goals.  

Olympia also offers Liquid Niagen®, an NAD+ precursor and injectable form of nicotinamide riboside (NR), for clinics and patients.  

Providers can open an account with Olympia to order NAD+ injections for their practice. Patients can start an order and our team will follow up with next steps, including your prescription.  

To get started, fill out the form below.