L-Carnitine

May aid in weight loss, improve physical performance and enhance overall well-being.

Dosage & Concentration

  • Dosage: 1 – 3 ml’s IV, 1 – 2 ml’s IM
  • Concentration: 500mg/ml

 

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Overview

Carnitine is found in nearly all cells of the body and plays a critical role in fueling the production of energy. It transports long-chain fatty acids into the mitochondria so they can be oxidized, or burned, to produce energy. Carnitine also transports toxic compounds out of the cellular organelle, preventing any accumulation. Given these functions, carnitine is concentrated in tissues that utilize fatty acids as fuel, like skeletal and cardiac muscles. For most people, the body makes a sufficient amount of carnitine, obtaining additional carnitine from their diets. However, some people have genetic or medical conditions that prevent their bodies from meeting the necessary needs. This is when supplementation by oral supplement or IV / IM is essential. Carnitine occurs in two forms known as D-carnitine and L-carnitine. They are isomers (or mirror images) of each other. D-carnitine is not used in lipid metabolism, while L-carnitine does. L-carnitine is the active form found in the body that transports fat to cells to be used as fuel in metabolic processes. L-carnitine is synthesized in the brain, liver, and kidneys from the amino acids methionine and lysine and is critical to heart and brain function, muscle movement, and several other body processes. Insufficient carnitine can lead to problems in the liver, heart, and muscles.

What Is Carnitine Prescribed For?

Carnitine is indicated in those with cardiovascular disease, renal (kidney) insufficiency, male infertility, diabetes, muscular disease, and HIV/AIDS.

Other Uses

May help turn fat into energy, which makes it an ideal supplement for fitness goals. L-Carnitine may help reduce muscle damage during resistance training.

Dosage, Concentration, Route of Administration

Dosage: Seek advice from an appropriately qualified and licensed physician, medical director or other healthcare provider

Concentration: 500mg/ml

Route of administration: IV, IM

Precautions/Side Effects

According to the National Institutes of Health, carnitine interacts with pivalate-conjugated antibiotics such as pivampicillin which are used in the treatment of urinary tract infections. Taking these antibiotics increases the excretion of pivaloyl-carnitine, which can lead to carnitine depletion. Carnitine also interacts with the anticonvulsants valproic acid, phenobarbital, phenytoin, or carbamazepine. Taking these have been shown to significantly decrease blood levels of carnitine. In addition, the use of valproic acid with or without other anticonvulsants may cause hepatotoxicity and increase plasma ammonia concentrations, leading to encephalopathy.

Some common side effects include:

  • – Nausea
  • – Vomiting
  • – Stuffy nose
  • – Diarrhea
  • – Restlessness
  • – Insomnia
  • – Body odor (“fishy” smell)

Some serious side effects may include:

  • – Tachycardia (fast heart rate)
  • – Hypertension (high blood pressure)
  • – Fever

Storage

Store at controlled room temperature. Protect from light.

 

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