Vitamin D is crucial to the building and maintenance of healthy bones and teeth. Calcium, the primary component of bone, is only properly absorbed by your body when vitamin D is present. Vitamin D is created within the body when direct sunlight converts a chemical in your skin into an active form of the vitamin. There are not many foods that contain vitamin D, but you can find it in fortified milk, fortified cereals, and fatty fish, like salmon, mackerel, and sardines. Unfortunately, most people do not get the necessary amount of vitamin D. Therefore, supplementation is needed. Vitamin D3 is the perfect supplement as it is the natural form of vitamin D that your body makes from sunlight.
What Is Cholecalciferol?
Vitamin D can come in several forms. The two major forms are vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).The recommended form of vitamin D for supplementation is cholecalciferol. Cholecalciferol is metabolized to its active form, calcitriol, which increases the body’s absorption of calcium and phosphorus. Some evidence suggests calcitriol plays a role in the immune system and may inhibit cancer growth and stimulate cell differentiation.
What Does Vitamin D3 Do In The Human Body?
Roles of vitamin D within the body, as stated by Medical News Today, include:
- – Support of the immune system, brain, and nervous system
- – Regulation of insulin levels, aiding in diabetes management
- – Support of lung function and cardiovascular health
- – Influence the expression of genes involved in cancer development
What Causes Vitamin D3 Deficiency?
Vitamin D deficiency is widespread globally and remains common in children and adults — an estimated 1 billion individuals are deficient worldwide. There are many different factors that affect the amount of vitamin D that your skin produces. These factors include the time of day, season, latitude, skin pigmentation, location, and lifestyle. Someone living in a state, such as Florida, would produce more vitamin D compared to someone living in a state with less sunshine. It is said that sunscreen, while important, can decrease vitamin D production because it blocks the UVB rays needed.
Vitamin D3 Injection Benefits
Receiving vitamin D3 injections can treat and prevent the symptoms of vitamin D deficiency, including fatigue and bone pain. Chronically low levels of vitamin D3 can lead to osteomalacia and rickets. Vitamin D deficiency has been associated with an increased risk of death from cardiovascular disease, cognitive impairment in the elderly, severe childhood asthma and cancer.
Vitamin D3 is indicated for those with cancer, dementia, multiple sclerosis, osteomalacia, osteoporosis, psoriasis, diabetes, and rickets.
When taken in appropriate doses, vitamin D is generally considered safe with no side effects. However, it can be harmful when taken in excess amounts. Some of the side effects experienced when taking too much include:
- – Nausea
- – Vomiting
- – Poor appetite
- – Constipation
- – Weakness
- – Weight loss
- – Confusion
- – Disorientation
- – Heart rhythm problems
- – Kidney damage
Vitamin D3 Injection Dosage
The recommended daily amount of vitamin D depends on age.
- – 0-12 months: 400 international units (IU)
- – 1 year – 70 years: 600 international units (IU)
- – Over 70 years: 800 international units (IU)
There are certain conditions that are contraindicated for the use of vitamin D3. These include:
- – Sarcoidosis
- – High phosphate blood levels
- – High calcium blood levels
- – Excessive vitamin D levels
- – Arteriosclerosis with occlusion of the arteries
- – Kidney stones
- – Kidney disease with reduced kidney function
- – Allergy to vitamin D
There are several possible interactions with vitamin D3. These include:
- – Aluminum
- – Anticonvulsants
- – Atorvastatin (Lipitor)
- – Calcipotriene (Dovonex)
- – Cholestyramine (Prevalite)
- – Cytochrome P450 3A4 (CYP3A4) substrates
- – Digoxin
- – Diltiazem (Cardizem, Tiazac)
- – Orlistat (Xenical, Alli)
- – Thiazide diuretics
- – Steroids
- – Stimulant laxatives
- – Verapamil (Verelan, Calan)
Always speak with your doctor when taking any new medication or supplementation. Always bring a list of medications or any other products you are taking with you for your healthcare provider to look over. If you experience any signs of overdose, seek medical attention immediately.
This product is available at our 503A/503B pharmacy.
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