Tirzepatide

Overview

Tirzepatide is a medication used primarily for managing type 2 diabetes and assisting with weight loss. It belongs to the class of drugs known as GLP-1 receptor agonists. What sets tirzepatide apart is its unique mechanism of action: it activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, two receptors that play key roles in regulating blood sugar levels.

What Is Tirzepatide Prescribed For?

Tirzepatide is primarily prescribed for managing type 2 diabetes. It enhances the body’s insulin production while simultaneously decreasing glucagon release, but only in the presence of glucose. This dual-action mechanism not only helps stabilize blood sugar levels but also prevents the dangerous peaks and valleys that can occur in diabetic patients.

Beyond its glucose-regulating capabilities, Tirzepatide has shown significant potential in aiding weight loss. Clinical trials have documented notable weight reduction in participants using this medication, which is particularly beneficial for individuals with type 2 diabetes. Excess weight can worsen insulin resistance, complicating diabetes management and increasing the risk of additional health complications.

What Is Compounded Tirzepatide?

Compounded tirzepatide refers to a drug formulation customized by a compounding pharmacy to meet specific patient needs, particularly when standard manufactured doses are unavailable or in short supply. This is often crucial during periods of drug shortages, which can hinder patient access to name-brand medications like Mounjaro®. Having access to compounded tirzepatide ensures that patients continue their treatment without interruption. By preparing specific doses customized for individual needs, pharmacists help sustain consistent treatment outcomes and prevent interruptions in medication dosages.

What Is Office Use Tirzepatide?

“Office use tirzepatide” refers to the practice of preparing and using tirzepatide within a healthcare setting, under the direct supervision of a medical professional, rather than dispensing it to patients for home use. This approach is typically employed in clinical settings such as hospitals or diabetes clinics where immediate administration is required or where closer monitoring of the patient’s response to the medication is necessary. This controlled approach allows healthcare providers to accurately manage dosing, observe the patient’s initial reactions, and modify treatment plans in real-time based on the patient’s immediate needs and the observed effects of the medication. This is particularly beneficial for patients with complex health issues or those starting a new treatment regimen.

At Olympia Pharmaceuticals, which operates both 503A and 503B facilities, we compound medications like tirzepatide for both office and home use. This flexibility ensures that essential treatments remain available, even during periods of drug shortages.

Dosage, Concentration and Route of Administration

Dosage: Seek advice from a licensed physician, medical director or other healthcare provider

Concentration (per mL): 25mg/mL

Volume: 3mL

Route of Administration: For SQ injection only

Storage

Store compounded tirzepatide at controlled refrigeration.

Prescribers and Physicians Order Form